Sourdough Pesto Grilled Cheese

Featured in: Simple Plates & Pairings

This elevated grilled cheese combines thick slices of sourdough bread with aromatic basil pesto and a luxurious blend of mozzarella, fontina, and sharp cheddar. Butter the bread, spread pesto on the interior, layer the cheeses, and grill until golden and melty. Total time: just 20 minutes for a vegetarian favorite that pairs perfectly with tomato soup or a fresh salad.

Updated on Tue, 20 Jan 2026 11:03:00 GMT
Golden-brown Sourdough Pesto Grilled Cheese slices oozing melted mozzarella and fontina on a rustic plate. Save
Golden-brown Sourdough Pesto Grilled Cheese slices oozing melted mozzarella and fontina on a rustic plate. | skilletindex.com

The smell of basil pesto hitting warm sourdough still stops me in my tracks, reminding me of rainy Tuesday afternoons when a simple grilled cheese felt like the only thing that could fix everything. I stumbled on this combination by accident one day when I was too hungry to make proper pesto pasta but had half a jar of pesto staring back at me from the fridge door.

My roommate walked in while I was flipping the first sandwich and immediately demanded I make her one too. That became our thing for months comfort food elevated just enough to feel special but simple enough for a Tuesday.

Ingredients

  • Thick cut sourdough bread: The sturdy texture holds up beautifully to the weight of three cheeses while developing that perfect golden crunch
  • Shredded mozzarella cheese: Provides the classic stringy melt that everyone loves in a grilled cheese
  • Shredded fontina cheese: Adds a subtle nuttiness and incredible creaminess that takes this beyond ordinary
  • Shredded sharp white cheddar: Brings a tangy punch that cuts through the richness of the other cheeses
  • Basil pesto: Spread thick on the inside it infuses every bite with fresh aromatic brightness
  • Unsalted butter softened: Creates that irresistible golden crust that makes sourdough sing when it hits the heat

Instructions

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Butter your bread slices:
Spread half a tablespoon of softened butter on one side of each sourdough slice making sure to cover every inch for even browning
Layer the pesto:
Flip the slices over and spread a generous tablespoon of basil pesto on the unbuttered side of only two slices
Add the cheese blend:
Divide all three cheeses evenly between the pesto covered slices creating layers that will melt into each other beautifully
Assemble the sandwiches:
Top each cheese piled slice with a remaining bread slice buttered side facing out like a golden promise
Heat your skillet:
Warm a large nonstick pan over medium heat until a drop of water sizzles and dances across the surface
Grill to perfection:
Cook for three to four minutes per side pressing gently with your spatula until the bread transforms into deep golden brown and cheese oozes slightly
Rest and serve:
Let the sandwiches cool for just one minute before slicing which helps the cheese set slightly so it does not completely escape when you cut
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A crispy Sourdough Pesto Grilled Cheese sandwich cut in half beside a bowl of tomato soup. Save
A crispy Sourdough Pesto Grilled Cheese sandwich cut in half beside a bowl of tomato soup. | skilletindex.com

This recipe became my go to for comfort feeding friends during tough times. Something about the combination of warm toasty bread and melty cheese feels like a hug in food form.

Making It Your Own

I have found that adding thin tomato slices between the cheese layers creates this wonderful brightness that cuts through the richness. Fresh baby spinach works beautifully too wilting slightly while adding color and nutrition.

Choosing The Right Pan

A cast iron skillet creates the most gorgeous crust but a good nonstick pan performs beautifully if you prefer easier cleanup. The key is giving the pan enough time to get properly hot before the sandwiches hit the surface.

Perfect Pairings

A simple side salad with bright vinaigrette balances the richness perfectly or go classic with tomato soup for the ultimate comfort meal experience.

  • Cut sandwiches on the diagonal for easier eating and that classic diner look
  • Letting them rest briefly keeps the cheese from running everywhere when you slice
  • Leftovers can be briefly reheated in a skillet to restore the crunch
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Close-up of a Sourdough Pesto Grilled Cheese revealing bright green basil pesto and sharp cheddar layers. Save
Close-up of a Sourdough Pesto Grilled Cheese revealing bright green basil pesto and sharp cheddar layers. | skilletindex.com

There is something profoundly satisfying about taking that first bite when the cheese is still molten and the bread is perfectly crisp.

Recipe FAQs

What type of sourdough bread works best?

Use thick-cut sourdough slices, about 1/2 inch thick. This prevents the bread from becoming too soft while the cheese melts and creates a better contrast between the crispy exterior and tender interior.

Can I make homemade pesto instead of store-bought?

Absolutely. Blend fresh basil, garlic, pine nuts, Parmesan, and olive oil to create your own pesto. Homemade versions often have a fresher, more vibrant flavor that elevates the sandwich.

What cheese alternatives work well?

Gruyère, provolone, and smoked gouda are excellent substitutes. You can also mix and match cheeses based on preference—just ensure they melt well and complement the pesto.

How do I prevent the cheese from leaking out?

Distribute the cheese evenly within the sandwich and don't overstuff. When grilling, press gently with a spatula to help the cheeses meld together without pushing them out the sides.

Can I add vegetables to this sandwich?

Yes. Thin tomato slices or fresh baby spinach work wonderfully. Add them after spreading the pesto to avoid sogginess. You can also include roasted red peppers or caramelized onions for depth.

What's the best way to reheat leftovers?

Use a skillet over medium heat rather than a microwave to maintain the bread's crispness. Heat for 2-3 minutes per side until the cheese is warm and the bread is toasted again.

Sourdough Pesto Grilled Cheese

Thick-cut sourdough layered with aromatic basil pesto and three melted cheeses, grilled until golden and crispy.

Prep Duration
10 minutes
Time to Cook
10 minutes
Overall Duration
20 minutes


Skill Level Easy

Cuisine Type American, Italian-inspired

Makes 2 Number of Servings

Diet Information Vegetarian Option

What You’ll Need

Bread

01 4 slices thick-cut sourdough bread

Cheese

01 1/2 cup shredded mozzarella cheese
02 1/2 cup shredded fontina cheese
03 1/2 cup shredded sharp white cheddar cheese

Spreads & Condiments

01 3 tablespoons basil pesto
02 2 tablespoons unsalted butter, softened

Method

Step 01

Prepare bread and butter: Lay out sourdough slices and spread 1/2 tablespoon softened butter on one side of each slice.

Step 02

Apply pesto and cheese: Flip bread over and spread approximately 1 tablespoon basil pesto on the unbuttered side of two slices. Evenly divide and layer mozzarella, fontina, and cheddar cheese over the pesto-covered slices.

Step 03

Assemble sandwiches: Top each prepared slice with remaining bread slices, ensuring buttered side faces outward.

Step 04

Heat cooking surface: Heat a large nonstick skillet or griddle over medium heat.

Step 05

Grill sandwiches: Place sandwiches in skillet and cook for 3 to 4 minutes per side, gently pressing with spatula until bread achieves golden-brown crispness and cheese melts completely.

Step 06

Rest and serve: Remove sandwiches from pan and allow 1 minute cooling time, then slice and serve warm.

Equipment Needed

  • Nonstick skillet or griddle
  • Spatula
  • Bread knife
  • Cheese grater

Allergy Details

Review every ingredient for possible allergens. When unsure, always check with a medical expert.
  • Wheat from sourdough bread
  • Milk from cheese and butter
  • Tree nuts potentially present in pesto

Nutrition details (each serving)

For your information only. Not a replacement for professional health advice.
  • Calorie count: 480
  • Fat content: 29 grams
  • Carbohydrates: 36 grams
  • Protein content: 19 grams